Depression and fatigue reinforce each other in a vicious cycle to European researchers. In a year long study of 3,200 patients, chances of experiencing fatigue for depressed patients went up four times, while the chances of depression more than doubled for fatigued patients.
Although doctors have long been aware of the link between the depression and unexplainable fatigue, no one is certain which comes first.
To find the, Skapinakis and two colleagues looked at a patient data from 14 countries as part of a World Health Organization study on psychological problems in general health care. "Fatigue and psychiatric disorder are not the same," Skapinakis says. "It is evident from the literature that fatigue and depression have different risk factors." He adds that these two conditions could overlap. Fatigue persons might feel psychologically distressed, while decreased energy is a symptom of depression.
Levels of physical activity could determine the correlation of fatigue and depression.
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